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10.2147/OAEM.S11862 http://scihub22266oqcxt.onion/10.2147/OAEM.S11862 C4753961!4753961 !27147846     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27147846 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Open+Access+Emerg+Med 2011 ; 3 (ä): 7-11 Nephropedia Template TP {{tp|p=27147846 |t=2011. Antimicrobial prophylaxis in open lower extremity fractures |pdf=|usr=}}{{27147846 }} gab.com Text Antimicrobial prophylaxis in open lower extremity fractures JO: Open Access Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=27147846 #FOAvip CLINICAL QUESTION: Based on the grade of open fracture, which antibiotic should be selected for antimicrobial prophylaxis, and what is the optimal timing and duration of administration? RESULTS: For Grade I and II open fractures, a first-generation cephalosporin (eg, cefazolin) should be administered within 3 hours of initial injury and be continued for 24 hours after initial injury. Grade III open fractures require coverage with an aminoglycoside in addition to a first-generation cephalosporin within 3 hours of initial injury, and antibiotics should be continued for 48-72 hours after initial injury but no more than 24 hours after wound closure. If a fracture is at risk of contamination with clostridium species, such as a farm-related injury, penicillin should be added to the antibiotic regimen. IMPLEMENTATION: Pitfalls to avoid when using antibiotics for infection prophylaxis in open fractures include utilizing cultures immediately postinjury to direct choice of agent for antimicrobial prophylaxis, because infecting pathogens do not typically correlate to pathogens initially cultured after injury; failure to consider patients' medication allergy history or reconcile allergy records; and failure to obtain a thorough history to determine injury exposure (eg, farm, water). Twit Text FOAVip Antimicrobial prophylaxis in open lower extremity fractures ????Open Access Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=27147846 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27147846 #FOAvip English Wikipedia <ref>{{Cite pmid|27147846 }}</ref> Antimicrobial prophylaxis in open lower extremity fractures #MMPMID27147846 Anderson A ; Miller AD ; Brandon Bookstaver P Open Access Emerg Med 2011[]; 3 (ä): 7-11 PMID27147846 show ga CLINICAL QUESTION: Based on the grade of open fracture, which antibiotic should be selected for antimicrobial prophylaxis, and what is the optimal timing and duration of administration? RESULTS: For Grade I and II open fractures, a first-generation cephalosporin (eg, cefazolin) should be administered within 3 hours of initial injury and be continued for 24 hours after initial injury. Grade III open fractures require coverage with an aminoglycoside in addition to a first-generation cephalosporin within 3 hours of initial injury, and antibiotics should be continued for 48-72 hours after initial injury but no more than 24 hours after wound closure. If a fracture is at risk of contamination with clostridium species, such as a farm-related injury, penicillin should be added to the antibiotic regimen. IMPLEMENTATION: Pitfalls to avoid when using antibiotics for infection prophylaxis in open fractures include utilizing cultures immediately postinjury to direct choice of agent for antimicrobial prophylaxis, because infecting pathogens do not typically correlate to pathogens initially cultured after injury; failure to consider patients' medication allergy history or reconcile allergy records; and failure to obtain a thorough history to determine injury exposure (eg, farm, water). äAntimicrobial prophylaxis in open lower extremity fractures (epmc).pdf DeepDyve Pubget Overpricing