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10.4103/2229-5070.175081

http://scihub22266oqcxt.onion/10.4103/2229-5070.175081
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C4778180!4778180!26998432
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suck abstract from ncbi


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pmid26998432      Trop+Parasitol 2016 ; 6 (1): 30-41
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  • Antimalarial drug resistance: An overview #MMPMID26998432
  • Antony HA; Parija SC
  • Trop Parasitol 2016[Jan]; 6 (1): 30-41 PMID26998432show ga
  • Malaria is a major public health burden throughout the world. Resistance to the antimalarial drugs has increased the mortality and morbidity rate that is achieved so far through the malaria control program. Monitoring the drug resistance to the available antimalarial drugs helps to implement effective drug policy, through the in vivo efficacy studies, in vitro drug susceptibility tests and detection of molecular markers. It is important to understand the mechanism of the antimalarial drugs, as it is one of the key factors in the emergence and spread of drug resistance. This review summarizes the commonly used antimalarial drugs, their mechanism of action and the genetic markers validated so far for the detection of drug-resistant parasites.
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