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2018 ; 7
(ä): 193
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Antibiotic treatment of acute gastroenteritis in children
#MMPMID29511533
Bruzzese E
; Giannattasio A
; Guarino A
F1000Res
2018[]; 7
(ä): 193
PMID29511533
show ga
Antibiotic therapy is not necessary for acute diarrhea in children, as
rehydration is the key treatment and symptoms resolve generally without specific
therapy. Searching for the etiology of gastroenteritis is not usually needed;
however, it may be necessary if antimicrobial treatment is considered. The latter
is left to the physician evaluation in the absence of clear indications.
Antimicrobial treatment should be considered in severely sick children, in those
who have chronic conditions or specific risk factors or in specific settings.
Traveler's diarrhea, prolonged diarrhea, and antibiotic-associated diarrhea may
also require antibiotic therapy. Depending on the severity of symptoms or based
on risk of spreading, empiric therapy may be started while awaiting the results
of microbiological investigations. The choice of antibiotic depends on suspected
agents, host conditions, and local epidemiology. In most cases, empiric therapy
should be started while awaiting such results. Empiric therapy may be started
with oral co-trimoxazole or metronidazole, but in severe cases parenteral
treatment with ceftriaxone or ciprofloxacin might be considered.
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