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2016 ; 6
(ä): 142
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Anti-Immune Strategies of Pathogenic Fungi
#MMPMID27896220
Marcos CM
; de Oliveira HC
; de Melo WC
; da Silva JF
; Assato PA
; Scorzoni L
; Rossi SA
; de Paula E Silva AC
; Mendes-Giannini MJ
; Fusco-Almeida AM
Front Cell Infect Microbiol
2016[]; 6
(ä): 142
PMID27896220
show ga
Pathogenic fungi have developed many strategies to evade the host immune system.
Multiple escape mechanisms appear to function together to inhibit attack by the
various stages of both the adaptive and the innate immune response. Thus, after
entering the host, such pathogens fight to overcome the immune system to allow
their survival, colonization and spread to different sites of infection.
Consequently, the establishment of a successful infectious process is closely
related to the ability of the pathogen to modulate attack by the immune system.
Most strategies employed to subvert or exploit the immune system are shared among
different species of fungi. In this review, we summarize the main strategies
employed for immune evasion by some of the major pathogenic fungi.