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10.1186/ar4402 http://scihub22266oqcxt.onion/10.1186/ar4402 C3979153!3979153 !24314231     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24314231 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Arthritis+Res+Ther 2013 ; 15 (6 ): 222 Nephropedia Template TP {{tp|p=24314231 |t=2013. Animal models of fibromyalgia |pdf=|usr=}}{{24314231 }} gab.com Text Animal models of fibromyalgia JO: Arthritis Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=24314231 #FOAvip Animal models of disease states are valuable tools for developing new treatments and investigating underlying mechanisms. They should mimic the symptoms and pathology of the disease and importantly be predictive of effective treatments. Fibromyalgia is characterized by chronic widespread pain with associated co-morbid symptoms that include fatigue, depression, anxiety and sleep dysfunction. In this review, we present different animal models that mimic the signs and symptoms of fibromyalgia. These models are induced by a wide variety of methods that include repeated muscle insults, depletion of biogenic amines, and stress. All potential models produce widespread and long-lasting hyperalgesia without overt peripheral tissue damage and thus mimic the clinical presentation of fibromyalgia. We describe the methods for induction of the model, pathophysiological mechanisms for each model, and treatment profiles. Twit Text FOAVip Animal models of fibromyalgia ????Arthritis Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=24314231 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24314231 #FOAvip English Wikipedia <ref>{{Cite pmid|24314231 }}</ref> Animal models of fibromyalgia #MMPMID24314231 DeSantana JM ; da Cruz KM ; Sluka KA Arthritis Res Ther 2013[]; 15 (6 ): 222 PMID24314231 show ga Animal models of disease states are valuable tools for developing new treatments and investigating underlying mechanisms. They should mimic the symptoms and pathology of the disease and importantly be predictive of effective treatments. Fibromyalgia is characterized by chronic widespread pain with associated co-morbid symptoms that include fatigue, depression, anxiety and sleep dysfunction. In this review, we present different animal models that mimic the signs and symptoms of fibromyalgia. These models are induced by a wide variety of methods that include repeated muscle insults, depletion of biogenic amines, and stress. All potential models produce widespread and long-lasting hyperalgesia without overt peripheral tissue damage and thus mimic the clinical presentation of fibromyalgia. We describe the methods for induction of the model, pathophysiological mechanisms for each model, and treatment profiles. |*Disease Models, Animal [MESH] |*Fibromyalgia [MESH]Animal models of fibromyalgia (epmc).pdf DeepDyve Pubget Overpricing