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10.3389/fphar.2017.00810 http://scihub22266oqcxt.onion/10.3389/fphar.2017.00810 C5682294!5682294 !29167642     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29167642 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Front+Pharmacol 2017 ; 8 (ä): 810 Nephropedia Template TP {{tp|p=29167642 |t=2017. An Update on AMPK in Hydrogen Sulfide Pharmacology |pdf=|usr=}}{{29167642 }} gab.com Text An Update on AMPK in Hydrogen Sulfide Pharmacology JO: Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=29167642 #FOAvip Hydrogen sulfide (H(2)S), the third bio-active gasotransmitter, is produced endogenously and tightly involved in the pathogenesis and treatment for various diseases. Adenosine 5'-monophosphate-activated protein kinase (AMPK) plays a paramount role in maintaining cellular energetic balance. Increasing evidences have also suggested AMPK as a novel modulator in multiple pathological conditions. In this paper, we will review the biological principles of H(2)S and AMPK, and most importantly, the recent discoveries regarding AMPK-mediated pharmacological actions of H(2)S. Emphasis will be laid on AMPK/H(2)S interactions in the cardiovascular system, autophagy, diabetic complications, and inflammation. In most cases described in this article, by promoting AMPK activation, H(2)S exerts cytoprotective effects or therapeutic potentials, though there remain some controversies before we can fully understand the involved mechanisms. Further researches are in need to investigate more closely any relationship between H(2)S and AMPK, and to put forward the development of H(2)S donors for clinical application. Twit Text FOAVip An Update on AMPK in Hydrogen Sulfide Pharmacology ????Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=29167642 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29167642 #FOAvip English Wikipedia <ref>{{Cite pmid|29167642 }}</ref> An Update on AMPK in Hydrogen Sulfide Pharmacology #MMPMID29167642 Wang M ; Tang W ; Zhu YZ Front Pharmacol 2017[]; 8 (ä): 810 PMID29167642 show ga Hydrogen sulfide (H(2)S), the third bio-active gasotransmitter, is produced endogenously and tightly involved in the pathogenesis and treatment for various diseases. Adenosine 5'-monophosphate-activated protein kinase (AMPK) plays a paramount role in maintaining cellular energetic balance. Increasing evidences have also suggested AMPK as a novel modulator in multiple pathological conditions. In this paper, we will review the biological principles of H(2)S and AMPK, and most importantly, the recent discoveries regarding AMPK-mediated pharmacological actions of H(2)S. Emphasis will be laid on AMPK/H(2)S interactions in the cardiovascular system, autophagy, diabetic complications, and inflammation. In most cases described in this article, by promoting AMPK activation, H(2)S exerts cytoprotective effects or therapeutic potentials, though there remain some controversies before we can fully understand the involved mechanisms. Further researches are in need to investigate more closely any relationship between H(2)S and AMPK, and to put forward the development of H(2)S donors for clinical application. äAn Update on AMPK in Hydrogen Sulfide Pharmacology (epmc).pdf DeepDyve Pubget Overpricing