Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24908482
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Neuron
2014 ; 82
(5
): 966-80
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Amygdala microcircuits controlling learned fear
#MMPMID24908482
Duvarci S
; Pare D
Neuron
2014[Jun]; 82
(5
): 966-80
PMID24908482
show ga
We review recent work on the role of intrinsic amygdala networks in the
regulation of classically conditioned defensive behaviors, commonly known as
conditioned fear. These new developments highlight how conditioned fear depends
on far more complex networks than initially envisioned. Indeed, multiple parallel
inhibitory and excitatory circuits are differentially recruited during the
expression versus extinction of conditioned fear. Moreover, shifts between
expression and extinction circuits involve coordinated interactions with
different regions of the medial prefrontal cortex. However, key areas of
uncertainty remain, particularly with respect to the connectivity of the
different cell types. Filling these gaps in our knowledge is important because
much evidence indicates that human anxiety disorders results from an abnormal
regulation of the networks supporting fear learning.
free
free
free
