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2020 ; 65
(3
): 72-75
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Alternative management of Covid-19 infection
#MMPMID32638647
Atrah HI
Scott Med J
2020[Aug]; 65
(3
): 72-75
PMID32638647
show ga
Cytokine storm is a life-threatening complication of Covid-19 infection.
Excessive cytokines are the products of hyperactive immune inflammatory response
mounted by the host against the virus. There is no agreed treatment for cytokine
storm. Three therapeutic agents with proven immune-modulatory properties in
regular use in a wide range of inflammatory disorders (high dose intravenous
immunoglobulin, Rituximab and thalidomide) are proposed for the treatment of
cytokine storm. Safety and efficacy of the proposed treatment should be assessed
by randomised controlled clinical trials. The use of the proposed treatment is
expected to reduce the mortality rate and alter the overall management of the
pandemic.