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10.3390/v7052321 http://scihub22266oqcxt.onion/10.3390/v7052321 C4452908!4452908 !25961488     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25961488 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Viruses 2015 ; 7 (5 ): 2321-33 Nephropedia Template TP {{tp|p=25961488 |t=2015. Alphaviruses in gene therapy |pdf=|usr=}}{{25961488 }} gab.com Text Alphaviruses in gene therapy JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=25961488 #FOAvip Alphavirus vectors present an attractive approach for gene therapy applications due to the rapid and simple recombinant virus particle production and their broad range of mammalian host cell transduction. Mainly three types of alphavirus vectors, namely naked RNA, recombinant particles and DNA/RNA layered vectors, have been subjected to preclinical studies with the goal of achieving prophylactic or therapeutic efficacy, particularly in oncology. In this context, immunization with alphavirus vectors has provided protection against challenges with tumor cells. Moreover, alphavirus intratumoral and systemic delivery has demonstrated substantial tumor regression and significant prolonged survival rates in various animal tumor models. Recent discoveries of the strong association of RNA interference and disease have accelerated gene therapy based approaches, where alphavirus-based gene delivery can play an important role. Twit Text FOAVip Alphaviruses in gene therapy ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=25961488 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25961488 #FOAvip English Wikipedia <ref>{{Cite pmid|25961488 }}</ref> Alphaviruses in gene therapy #MMPMID25961488 Lundstrom K Viruses 2015[May]; 7 (5 ): 2321-33 PMID25961488 show ga Alphavirus vectors present an attractive approach for gene therapy applications due to the rapid and simple recombinant virus particle production and their broad range of mammalian host cell transduction. Mainly three types of alphavirus vectors, namely naked RNA, recombinant particles and DNA/RNA layered vectors, have been subjected to preclinical studies with the goal of achieving prophylactic or therapeutic efficacy, particularly in oncology. In this context, immunization with alphavirus vectors has provided protection against challenges with tumor cells. Moreover, alphavirus intratumoral and systemic delivery has demonstrated substantial tumor regression and significant prolonged survival rates in various animal tumor models. Recent discoveries of the strong association of RNA interference and disease have accelerated gene therapy based approaches, where alphavirus-based gene delivery can play an important role. |*Transduction, Genetic [MESH] |Alphavirus/*genetics [MESH] |Cancer Vaccines/administration & dosage [MESH] |Drug Carriers/*administration & dosage [MESH] |Genetic Therapy/*methods [MESH] |Humans [MESH]Alphaviruses in gene therapy (epmc).pdf DeepDyve Pubget Overpricing