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2018 ; 10
(2
): ä Nephropedia Template TP
gab.com Text
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English Wikipedia
Alginate in Wound Dressings
#MMPMID29614804
Aderibigbe BA
; Buyana B
Pharmaceutics
2018[Apr]; 10
(2
): ä PMID29614804
show ga
Alginate is a biopolymer used in a variety of biomedical applications due to its
favourable properties, such as biocompatibility and non-toxicity. It has been
particularly attractive in wound healing applications to date. It can be tailored
to materials with properties suitable for wound healing. Alginate has been used
to prepare different forms of materials for wound dressings, such as hydrogels,
films, wafers, foams, nanofibres, and in topical formulations. The wound
dressings prepared from alginate are able to absorb excess wound fluid, maintain
a physiologically moist environment, and minimize bacterial infections at the
wound site. The therapeutic efficacy of these wound dressings is influenced by
the ratio of other polymers used in combination with alginate, the nature of
cross linkers used, the time of crosslinking, nature of excipients used, the
incorporation of nanoparticles, and antibacterial agents. This review provides a
comprehensive overview of the different forms of wound dressings containing
alginate, in vitro, and in vivo results.