Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26646075
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMC+Med
2015 ; 13
(ä): 293
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Advances in the treatment of newly diagnosed glioblastoma
#MMPMID26646075
Theeler BJ
; Gilbert MR
BMC Med
2015[Dec]; 13
(ä): 293
PMID26646075
show ga
Glioblastoma is a refractory malignancy with limited treatment options at tumor
recurrence. Only a small proportion of patients survive 2 years or longer with
the current standard of care. Gene expression profiling can segregate newly
diagnosed patients into groups with different prognoses, and these biomarkers are
being incorporated into a new generation of personalized clinical trials. Using
the experience from recently completed large scale, multi-faceted, randomized
glioblastoma clinical trials, a new clinical trial paradigm is being established
to move promising therapies forward into the newly diagnosed treatment setting.
Upcoming trials using the immune check-point inhibitors are an example of this
changing paradigm and these and other immunotherapies have potential as promising
new treatment modalities for newly diagnosed GB patients.