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2015 ; 7
(ä): 53
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Advances in the management of basal cell carcinoma
#MMPMID26097726
Lewin JM
; Carucci JA
F1000Prime Rep
2015[]; 7
(ä): 53
PMID26097726
show ga
Basal cell carcinoma (BCC), a malignant neoplasm derived from non-keratinizing
cells that originate in the basal layer of the epidermis, is the most common
cancer in humans. Several factors such as anatomic location, histologic features,
primary or recurrent tumors, and patient characteristics influence the choice of
treatment modality for BCC. Mohs micrographic surgery (MMS) facilitates optimal
margin control and conservation of normal tissue for the management of BCC;
however, other treatment modalities may also be implemented in the correct
clinical scenario. Other treatment modalities that will be reviewed include
simple excision, electrodesiccation and curettage, cryotherapy, topical
immunotherapy and chemotherapy, photodynamic therapy, and radiation therapy. In
addition, targeted molecular therapeutic options for the treatment of advanced or
metastatic BCC will be discussed in this informal review based on recent
literature obtained by using PubMed with relevant search terms.
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