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2014 ; 2014
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Acute otitis media in children
#MMPMID25229555
Venekamp RP
; Damoiseaux RA
; Schilder AG
BMJ Clin Evid
2014[Sep]; 2014
(ä): ä PMID25229555
show ga
INTRODUCTION: Acute otitis media (AOM) is a common reason for primary care visits
in children. Yet, there is considerable debate on the most effective treatment.
METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the
following clinical questions: What are the effects of treatments (analgesics,
antibiotics, and myringotomy) in children with AOM? We searched: Medline, Embase,
The Cochrane Library, and other important databases up to October 2013 (Clinical
Evidence reviews are updated periodically; please check our website for the most
up-to-date version of this review). We included harms alerts from relevant
organisations such as the US Food and Drug Administration (FDA) and the UK
Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 17
studies that met our inclusion criteria. We performed a GRADE evaluation of the
quality of evidence for interventions. CONCLUSIONS: In this systematic review we
present information relating to the effectiveness and safety of the following
interventions: analgesics, antibiotics, delayed antibiotics, immediate
antibiotics, longer courses of antibiotics, and myringotomy.
|*Middle Ear Ventilation
[MESH]
|Analgesics/*therapeutic use
[MESH]
|Anti-Bacterial Agents/administration & dosage/*therapeutic use
[MESH]