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2017 ; 6
(3
): 162-167
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Acute kidney injury from different poisonous substances
#MMPMID28540206
Naqvi R
World J Nephrol
2017[May]; 6
(3
): 162-167
PMID28540206
show ga
AIM: To report our experience of acute kidney injury (AKI) developed after
exposure to poisonous substance. METHODS: Retrospective study where data was
collected from case records of patients coming to this institute during January
1990 to May 2016. This institution is a tertiary care center for renal care in
the metropolitan city of Karachi, Pakistan. History of ingested substance,
symptoms on presentation, basic laboratory tests on arrival, mode of treatment
and outcome were recorded from all patients and are presented here. Patients
developing AKI after snake envenomation or scorpion stings are not included in
this study. RESULTS: During studied period 184 cases of AKI developing after
poisoning were seen at our institution. The largest group was from paraphenyline
diamine poisoning comprising 135 patients, followed by methanol in 8,
organophosphorus compounds in 5, paraquat in 5, copper sulphate in 5, tartaric
acid in 4, phenobarbitone in 3 and benzodiazipines, datura, rat killer, fish gall
bladder, arsenic, boiler water, ammonium dichromate, acetic acid and herbs with
lesser frequency. In 8 patients multiple substances were ingested in combination.
Renal replacement therapy was required in 96% of patients. Complete recovery was
seen in 72.28% patients, 20% died during acute phase of illness. CONCLUSION: It
is important to report poisonous substances causing vital organ failure to
increase awareness among general population as well as health care providers.