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10.1177/204946370900300204

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suck abstract from ncbi


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pmid26525109
      Rev+Pain 2009 ; 3 (2 ): 10-4
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  • Acute Pain Management in Opioid Dependent Patients #MMPMID26525109
  • Mehta V ; Langford R
  • Rev Pain 2009[Oct]; 3 (2 ): 10-4 PMID26525109 show ga
  • Acute pain management remains a challenge in opioid dependent patients, and it has been recognised that these patients are commonly under-treated.Chronic opioid exposure leads to widespread adaptations both at cellular and synaptic level.Physical dependence is a neuropharmacological phenomenon as a result of neuroadaptation and neuroplasticity, in contrast to addiction that is both neuropharmacological and behavioural.While providing the patient's pre-existing opioid requirement, the acute pain episode should be managed using additional multimodal analgesia: non-opioid medications in combination with local anaesthetic techniques and as required, short-acting opioid titrated to effect.Patients on long term buprenorphine and methadone with acute pain episode should be continued with their maintenance therapy and an additional short-acting opioid analgesic titrated to achieve therapeutic effect.
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