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2009 ; 3
(2
): 10-4
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Acute Pain Management in Opioid Dependent Patients
#MMPMID26525109
Mehta V
; Langford R
Rev Pain
2009[Oct]; 3
(2
): 10-4
PMID26525109
show ga
Acute pain management remains a challenge in opioid dependent patients, and it
has been recognised that these patients are commonly under-treated.Chronic opioid
exposure leads to widespread adaptations both at cellular and synaptic
level.Physical dependence is a neuropharmacological phenomenon as a result of
neuroadaptation and neuroplasticity, in contrast to addiction that is both
neuropharmacological and behavioural.While providing the patient's pre-existing
opioid requirement, the acute pain episode should be managed using additional
multimodal analgesia: non-opioid medications in combination with local
anaesthetic techniques and as required, short-acting opioid titrated to
effect.Patients on long term buprenorphine and methadone with acute pain episode
should be continued with their maintenance therapy and an additional short-acting
opioid analgesic titrated to achieve therapeutic effect.