Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26468309
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26468309
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Viszeralmedizin
2015 ; 31
(3
): 163-5
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Acute Cholecystitis
#MMPMID26468309
Schuld J
; Glanemann M
Viszeralmedizin
2015[Jun]; 31
(3
): 163-5
PMID26468309
show ga
BACKGROUND: The treatment of acute cholecystitis has been controversially
discussed in the literature as there are no high-evidence-level data yet for
determining the optimal point in time for surgical intervention. So far, the
laparoscopic removal of the gallbladder within 72 h has been the most preferred
approach in acute cholecystitis. METHODS: We conducted a systematic review by
including randomized trials of early laparoscopic cholecystectomy for acute
cholecystitis. RESULTS: Based on a few prospective studies and two meta-analyses,
there was consent to prefer an early laparoscopic cholecystectomy for patients
suffering from acute calculous cholecystitis while the term 'early' has not been
consistently defined yet. So far, there is new level 1b evidence brought forth by
the so-called 'ACDC' study which has convincingly shown in a prospective
randomized setting that immediate laparoscopic cholecystectomy - within a time
frame of 24 h after hospital admission - is the smartest approach in ASA I-III
patients suffering from acute calculous cholecystitis compared to a more
conservative approach with a delayed laparoscopic cholecystectomy after an
initial antibiotic treatment in terms of morbidity, length of hospital stay, and
overall treatment costs. Concerning critically ill patients suffering from acute
calculous or acalculous cholecystitis, there is no consensus in treatment due to
missing data in the literature. CONCLUSION: Laparoscopic cholecystectomy for
acute cholecystitis within 24 h after hospital admission is a safe procedure and
should be the preferred treatment for ASA I-III patients. In critically ill
patients, the intervention should be determined by a narrow interdisciplinary
consent based on the patient's individual comorbidities.