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2014 ; 43
(5
): 556-60
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Actinomycosis in Iran: Short Narrative Review Article
#MMPMID26060757
Khodavaisy S
; Zibafar E
; Hashemi SJ
; Narenji H
; Daie Ghazvini R
Iran J Public Health
2014[May]; 43
(5
): 556-60
PMID26060757
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Actinomycosis is an indolent, slowly progressive infection caused by anaerobic or
microaerophilic bacteria, primarily of genus Actinomyces, which colonize the
mouth, colon and vagina. Mucosal disruption may lead to infection virtually at
any sites in the body. The aim of this study was to underline different features
of actinomycosis and to represent total data about etiologic agents, clinical,
diagnostic and therapeutic approaches these infections. From a total of 38 case
reports or series, ninety one cases were obtained by using of relevant articles
reported as recorded cases in Iran (1972 to 2012). Analyzed data represented 21
cases of oral-servicofacial (23.1%), 7 cases of thoracic (7.7%), 17 cases of
abdominal (18.7%), 21 cases of disseminated forms (23.1%) and 25 cases of others
(27.5%). Findings indicated more common of these infections in men (61.5%).
Actinomyces naeslundii (21 cases) was found as the most common causative agents
in comparison with A. Israeli (15 cases), A. viscosus (3 cases) and A. bovis (1
case). The most patients had been successfully treated with penicillin although
some cases needed surgery along with antibiotic therapy. Since some clinical
features of actinomycosis are similar to malignancies, so the differential
diagnosis of invasive forms must be considered. This report emphasizes on the
importance of differential diagnosis of actinomycosis from similar diseases by
clinicians.
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