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2016 ; 2
(4
): 140-142
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Acral self-healing collodion baby: A case series
#MMPMID28492026
Ferrari B
; Martínez JP
; Luna PC
; Larralde M
Int J Womens Dermatol
2016[Dec]; 2
(4
): 140-142
PMID28492026
show ga
Collodion baby is a term used to describe a phenotype characterized by the
presence of a tight, translucent membrane that covers the entire skin at birth.
This membrane usually sheds around 10 to 14 days and reveals the underlying
disease (mainly different types of Recessive Ichthyosis or other infrequent
disorders). A rare variant of this phenotype is known as acral self-healing
collodion baby whereby the patients are born with the typical membrane but
limited to the hands and feet only, and after it sheds, the skin appears
completely normal. We report five cases of this very rare subtype of collodion
baby. All the patient cases that are presented involved both hands and feet. One
of the patients also had the umbilicus embedded in a subtle collodion membrane.
None of the patients had a family history of the same entity or any other type of
ichthyosis. In all patients, the condition resolved spontaneously within a few
weeks and no patients developed any other manifestation. Although no molecular
analysis was performed, we contribute to the knowledge of the clinical features
of this extremely uncommon and benign entity, since to the best of our knowledge
there are only two previous reports available in literature.