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2014 ; 49
(1
): 13-6
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Acne vulgaris
#MMPMID26078626
Aydemir EH
Turk Pediatri Ars
2014[Mar]; 49
(1
): 13-6
PMID26078626
show ga
Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit and it
is observed equally in both sexes and nearly all races. It generally begins at
puberty, but the healing period is variable. There is no known etiological
factor, except genetic tendency. Androgens play a very limited role in some
female patients. The effects of cosmetics, foods and drinks are also discussible
and too limited. There are four factors in acne pathogenesis: Increase of the
sebum excretionKeratinization of infrainfundibulumBacterial colonization of the
follicleInflammation It is mainly observed on the face and back, shoulders and
chest. Initial lesions are comedons. Papules, pustules and cysts of severe types
follow it. The most important factor in treatment is a very good
patient-physician communication. Topical or systemic treatment or both can be
used depending on the severity of acne. Benzoyl peroxyde, azelaic acid, AHA's
antibiotics, retinoic acid and derivatives are the topical choices. For systemic
treatment antibiotics are the most commonly used medicines, but isotretinoine has
a very spesific place with the possibility of permanent healing. All kind of
treatments need approximately six months for a good result.