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1986 ; 1
(1
): 60-6
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A study on cerebral embolism in mitral stenosis
#MMPMID15759378
Kwon O
; Kim MH
; Kim KS
; Bae JH
; Kim MS
; Song JS
Korean J Intern Med
1986[Jan]; 1
(1
): 60-6
PMID15759378
show ga
To evaluate the significance of episodes of cerebral embolism in patients with
mitral valve disease in Korea, 128 patients with echocardiographic diagnosis of
mitral valve disease were examined. Among these, 82 patients had predominant
mitral stenosis. 1. The clinical features of 82 patients with mitral stenosis
have been reviewed to elucidate the factors favoring cerebral embolism which
occurred in 19 patients, i.e., incidence of 23.2%. 2. Atrial fibrillation was
present in 16 of 19 patients with cerebral embolism (84.2%). Cerebral embolic
episodes occurred in 16 of 47 patients with atrial fibrillation (34.0%). 3. The
mean age (55.3 ± 12.1 years) of patients without cerebral embolism was
significantly older than that (43.2 ± 14.6 years) of patients without cerebral
embolism (P<0.005). 4. There was no significant relationship between the
incidence of embolism and sex, left atrial thrombi, left atrium/aortic root
diameter, mitral valvular orifice area, mitral valvular vegetation or
calcification, left ventricular enddiastolic dimension or left ventricular
posterior wall thickness. Cerebral embolism is common in patients with mitral
stenosis in our country. The presence of atrial fibrillation and low cardiac
output increase the attack of cerebral emboli whereas the severity of mitral
stenosis, as judged by valve area, may not correlate with the occurrence of
emboli. The best treatment for cerebral embolism is prevention. Therefore, we
believe that more vigorous treatment of patients with mitral valve disease who
are old or associated with atrial fibrillation as well as previous embolic
history is indicated.
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