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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Biol+Chem
2017 ; 292
(35
): 14704-14705
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A new modification for mammalian messenger RNA
#MMPMID28864714
Liu F
; He C
J Biol Chem
2017[Sep]; 292
(35
): 14704-14705
PMID28864714
show ga
The discovery of multiple RNA modifications in the past few years has broadened
our views of the structures and potential functions of RNA species, but
deciphering which modifications are made where and how remains a challenge. A new
study by Xu et al. applies a combination of mass spectrometry, biochemistry,
genetics, and cellular biology tools to reveal the two mammalian
methyltransferases that are responsible for m(3)C installation in tRNA and a
third that mediates the previously unknown installation of m(3)C in mammalian
mRNA.