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10.1002/jnr.23773 http://scihub22266oqcxt.onion/10.1002/jnr.23773 C5027969!5027969 !27638591     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27638591 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Neurosci+Res 2016 ; 94 (11 ): 1049-61 Nephropedia Template TP {{tp|p=27638591 |t=2016. A microglial hypothesis of globoid cell leukodystrophy pathology |pdf=|usr=}}{{27638591 }} gab.com Text A microglial hypothesis of globoid cell leukodystrophy pathology JO: J Neurosci Res http://www.kidney.de/pget.php?&tw=1&pmid=27638591 #FOAvip Globoid cell leukodystrophy (GLD), also known as Krabbe's disease, is a fatal demyelinating disease accompanied by the formation of giant, multinucleated cells called globoid cells. Previously believed to be a byproduct of inflammation, these cells can be found early in disease before evidence of any damage. The precise mechanism by which these globoid cells cause oligodendrocyte dysfunction is not completely understood, nor is their cell type defined. This Review outlines the idea that microglial cells are transformed into an unknown and undefined novel M3 phenotype in GLD, which is cytotoxic to oligodendrocytes, leading to disease progression. © 2016 Wiley Periodicals, Inc. Twit Text FOAVip A microglial hypothesis of globoid cell leukodystrophy pathology ????J Neurosci Res http://www.kidney.de/pget.php?&tw=1&pmid=27638591 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27638591 #FOAvip English Wikipedia <ref>{{Cite pmid|27638591 }}</ref> A microglial hypothesis of globoid cell leukodystrophy pathology #MMPMID27638591 Nicaise AM ; Bongarzone ER ; Crocker SJ J Neurosci Res 2016[Nov]; 94 (11 ): 1049-61 PMID27638591 show ga Globoid cell leukodystrophy (GLD), also known as Krabbe's disease, is a fatal demyelinating disease accompanied by the formation of giant, multinucleated cells called globoid cells. Previously believed to be a byproduct of inflammation, these cells can be found early in disease before evidence of any damage. The precise mechanism by which these globoid cells cause oligodendrocyte dysfunction is not completely understood, nor is their cell type defined. This Review outlines the idea that microglial cells are transformed into an unknown and undefined novel M3 phenotype in GLD, which is cytotoxic to oligodendrocytes, leading to disease progression. © 2016 Wiley Periodicals, Inc. |Animals [MESH] |Humans [MESH] |Leukodystrophy, Globoid Cell/*pathology [MESH]A microglial hypothesis of globoid cell leukodystrophy pathology (epmc).pdf DeepDyve Pubget Overpricing