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2017 ; 84
(ä): 35-39
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A beginner s guide to tissue clearing
#MMPMID28082099
Ariel P
Int J Biochem Cell Biol
2017[Mar]; 84
(ä): 35-39
PMID28082099
show ga
The last decade has seen a proliferation of tissue clearing methods that render
large biological samples transparent and allow unprecedented three-dimensional
views of enormous volumes of tissue. For a scientist wondering whether these
methods will be useful to address their research problems, it can be bewildering
to sort through the ever-increasing number of papers introducing new clearing
methods. Here, I provide a concise summary for the novice describing what tissue
clearing is, which research problems it can be applied to, how to decide on a
clearing method, and where the field is headed in the future.