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2015 ; 8
(4
): 53-9
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A Review on Noma: A Recent Update
#MMPMID26573028
Ashok N
; Tarakji B
; Darwish S
; Rodrigues JC
; Altamimi MA
Glob J Health Sci
2015[Jul]; 8
(4
): 53-9
PMID26573028
show ga
Noma is a gangrenous infection primarily affecting under developed countries. The
aim of this paper was to review all recent articles on noma from January 2003 to
August 2014 and briefly update the latest information related to the topic. A
literature search was done on PUBMED using the keywords "noma/cancrum oris". Noma
is commonly seen in malnourished children. There has been an increased incidence
of noma in HIV patients. Apart from these, noma has also been reported in
association with cyclic neutropenia, herpetic stomatitis, leukemia, Down's
syndrome and Burkett's disease. Treatment of acute noma includes transfusion of
blood and intravenous fluids, administration of antibiotics, putting the patient
on a high protein diet and debridement of necrotic areas. Surgical phase is
usually initiated 6 to 18 months after a period of quiescence. Although, the
mortality rate associated with noma has reduced significantly with the advent of
modern generation antibiotics, the functional, cosmetic and psychological
challenges associated with the destruction of soft or hard tissues still remains
a huge challenge. Adequate steps must be implemented by the government or medical
professionals to prevent the disease and provide an early intervention.
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