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2015 ; 22
(2
): 83-6
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A First Case of Osteomesopyknosis in Korea
#MMPMID26082918
Jeoung BN
; Kim JM
; Kang GE
; Lim JH
; Kim EH
; Seo HA
J Bone Metab
2015[May]; 22
(2
): 83-6
PMID26082918
show ga
Osteomesopyknosis is a rare sclerosing bone disorder of autosomal dominant
inheritance. We report a first case of osteomesopyknosis in Korea. A 16-year old
girl complained of diffuse back pain for 1 year. We performed physical
examination, biochemical investigations and imaging studies. A radiograph of
spine revealed rugger-jersey vertebra and sandwich vertebra. Bone specific
alkaline phosphatase, osteocalcin and C-terminal telopeptides of type I collagen
were normal. Only an axial skeleton involvement was shown on the whole body bone
scan. This patient was diagnosed to have osteomesopyknosis. Osteomesopyknosis is
characterized by normal level of bone turnover marker and an axial bone
involvement. Osteomesopyknosis can be occurred in Korea and needs to be
considered when patients, especially young patients, suffer from back pain and
have only axial osteosclerosis.