Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29632756
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cureus
2018 ; 10
(2
): e2147
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
A Case of IgG4-related Sclerosing Mesenteritis
#MMPMID29632756
Butt Z
; Alam SH
; Semeniuk O
; Singh S
; Chhabra GS
; Tan IJ
Cureus
2018[Feb]; 10
(2
): e2147
PMID29632756
show ga
A 60-year-old African-American male presented to the emergency department with
abdominal pain and distention associated with decreased appetite and weight loss
for several weeks. A computed tomography (CT) scan of the abdomen and pelvis
showed an 8 cm mesenteric mass with surrounding stranding and poorly defined
borders. The patient underwent exploratory laparotomy and complete resection of
the mass since the frozen section could not give a definite diagnosis.
Histopathology showed fibro-adipose tissue with lymphoid hyperplasia, vague
nodular collections of foamy histiocytes with giant cell reaction, marked chronic
inflammation, fat necrosis, and prominent sclerosis/fibrosis. Methenamine silver
and acid-fast stains were negative for fungal and mycobacterial organisms
respectively. Examination of tissue with immunohistostains showed increased
immunoglobulin G4 (IgG4)-positive plasma cells. Other features observed were
scattered areas of phlebitis, pockets of tissue eosinophilia, and focal storiform
fibrosis leading to the diagnosis of IgG4-related sclerosing mesenteritis. The
patient did not require steroids after the surgical resection and was disease
free at six-month follow up.
free
free
free
