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2017 ; 22
(5
): 542-548
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A Bacterial Cause of Cancer: An Historical Essay
#MMPMID28432224
Lichtman MA
Oncologist
2017[May]; 22
(5
): 542-548
PMID28432224
show ga
This article reviews the history of the discovery of microbes that increase the
risk of cancer of some tissues with a special emphasis on the bacterium
Helicobacter pylori and the role played by two Australian physicians, neither
schooled in research, who had open minds about the shibboleth that mycobacteria
(acid-fast organisms) can survive the acid environment of the stomach, but that
other pathogenic bacteria cannot. They discovered one of the most important human
pathogens, Helicobacter pylori, and showed it capable of inducing severe gastric
inflammatory disease. Subsequently, others built on their observations and showed
it capable of inducing two gastric neoplasms: carcinoma and lymphoma. The
Oncologist 2017;22:542-548.