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2006 ; 56
(6
): 1274-82
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9 4T human MRI: preliminary results
#MMPMID17075852
Vaughan T
; DelaBarre L
; Snyder C
; Tian J
; Akgun C
; Shrivastava D
; Liu W
; Olson C
; Adriany G
; Strupp J
; Andersen P
; Gopinath A
; van de Moortele PF
; Garwood M
; Ugurbil K
Magn Reson Med
2006[Dec]; 56
(6
): 1274-82
PMID17075852
show ga
This work reports the preliminary results of the first human images at the new
high-field benchmark of 9.4T. A 65-cm-diameter bore magnet was used together with
an asymmetric 40-cm-diameter head gradient and shim set. A multichannel
transmission line (transverse electromagnetic (TEM)) head coil was driven by a
programmable parallel transceiver to control the relative phase and magnitude of
each channel independently. These new RF field control methods facilitated
compensation for RF artifacts attributed to destructive interference patterns, in
order to achieve homogeneous 9.4T head images or localize anatomic targets. Prior
to FDA investigational device exemptions (IDEs) and internal review board
(IRB)-approved human studies, preliminary RF safety studies were performed on
porcine models. These data are reported together with exit interview results from
the first 44 human volunteers. Although several points for improvement are
discussed, the preliminary results demonstrate the feasibility of safe and
successful human imaging at 9.4T.
|*Transducers
[MESH]
|Burns, Electric/etiology/prevention & control
[MESH]
free
free
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