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Radically novel prostaglandins in animals and plants: the isoprostanes Mueller MJChem Biol 1998[Dec]; 5 (12): R323-33Animal prostaglandins and plant jasmonates are well-known enzymatically formed cyclopentanoic lipids that have regulatory functions and serve as inducible mediators of host defense reactions. A novel group of prostaglandin-like compounds, the isoprostanes, generated in animals and plants by a nonenzymatic, free radical-catalyzed process, are now suspected to be mediators of oxidant injury in vivo.|*Cyclopentanes[MESH]|Animals[MESH]|Catalysis[MESH]|Free Radicals[MESH]|Models, Chemical[MESH]|Oxidative Stress[MESH]|Oxylipins[MESH]|Plant Growth Regulators/*physiology[MESH]|Plants[MESH]|Prostaglandin-Endoperoxide Synthases/metabolism[MESH]|Prostaglandins/*physiology[MESH]|Protein Sorting Signals[MESH] |
