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A catalogue of imprinted genes and parent-of-origin effects in humans and animals Morison IM; Reeve AEHum Mol Genet 1998[]; 7 (10): 1599-609Parent-of-origin effects were first recorded >3000 years ago by mule breeders in Asia Minor. There are now several different types of evidence suggesting the presence of a large number of imprinted genes, many of which have not yet been identified. Here, we catalogue a wide range of evidence and phenomena which indicate or suggest the presence of genomic imprinting in animals. This evidence includes: the direct documentation of parent-of-origin-specific gene transcription; human disease inheritance patterns which suggest the involvement of imprinted genes; and older, less well studied animal models which may show parent-of-origin effects.|*Genomic Imprinting[MESH]|Animals[MESH]|Chromosome Mapping[MESH]|Chromosomes, Human/genetics[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Models, Genetic[MESH]|Phenotype[MESH] |
