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lüll Nucleocytoplasmic transport: driving and directing transport Cole CN; Hammell CMCurr Biol 1998[May]; 8 (11): R368-72Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport.|*Cell Cycle Proteins[MESH]|*GTPase-Activating Proteins[MESH]|*Guanine Nucleotide Exchange Factors[MESH]|Animals[MESH]|Biological Transport, Active[MESH]|Carrier Proteins/metabolism[MESH]|Cell Nucleus/*metabolism[MESH]|Cytoplasm/*metabolism[MESH]|DNA-Binding Proteins/metabolism[MESH]|GTP Phosphohydrolases/metabolism[MESH]|Guanosine Diphosphate/metabolism[MESH]|Guanosine Triphosphate/metabolism[MESH]|Models, Biological[MESH]|Nuclear Proteins/metabolism[MESH]|Saccharomyces cerevisiae/metabolism[MESH]|ran GTP-Binding Protein[MESH] |