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Vascular permeability factor/vascular endothelial growth factor and vascular stroma formation in neoplasia Insights from in situ hybridization studies Brown LF; Guidi AJ; Tognazzi K; Dvorak HFJ Histochem Cytochem 1998[May]; 46 (5): 569-75The formation of vascular stroma plays an important role in the pathophysiology of malignancy. We describe the use of in situ hybridization in our laboratory as a tool to study the role of vascular permeability factor/vascular endothelial growth factor in the angiogenesis associated with malignancy.|Animals[MESH]|Endothelial Growth Factors/*physiology[MESH]|Endothelium, Vascular/*pathology[MESH]|Humans[MESH]|In Situ Hybridization[MESH]|Lymphokines/*physiology[MESH]|Neoplasms/*blood supply/pathology[MESH]|Neovascularization, Pathologic[MESH]|Stromal Cells/pathology[MESH]|Vascular Endothelial Growth Factor A[MESH]|Vascular Endothelial Growth Factors[MESH] |