Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll A retrospective review of yttrium-90 synovectomy in the treatment of knee arthritis Taylor WJ; Corkill MM; Rajapaske CNBr J Rheumatol 1997[Oct]; 36 (10): 1100-5We reviewed the case notes and X-rays of all patients with knee arthritis treated with yttrium-90 for the first time at a single institution from November 1981 to November 1995. Outcomes were assessed as 'improved' or 'not improved' by review of the case notes at 3, 6 and 12 months, and by the absence of further intra-articular (IA) steroid injections. Of the 121 knees treated, 87 had adequate follow-up information to allow an assessment of outcomes. Overall, 46% (95% CI 36-57) were improved at 12 months and 37% (95% CI 27-47) had no further IA injections (mean follow-up of 3.5 yr). Knees with osteoarthritis (OA) fared significantly worse with 10% (95% CI 0-29) vs 51% (95% CI 39-63) improved at 12 months (P < 0.05). Knees younger than 30 appeared to do better with 78% (95% CI 51-100) vs 28% (95% CI 17-45) having no further IA injections (P < 0.02). Knees with normal X-rays (Kellgren grade 0-1) did significantly better than those with more severe radiographic abnormalities (Kellgren grade 3-4), with 56% (95% CI 40-73) vs 24% (95% CI 8-40) improved (P < 0.01). Radiosynovectomy with yttrium-90 for knee arthritis appears to be of less value for patients with OA or with secondary OA changes on X-ray, and may be of more value for younger patients and those with spondyloarthropathies.|*Synovectomy[MESH]|Adult[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Arthritis/drug therapy/physiopathology/*surgery[MESH]|Combined Modality Therapy[MESH]|Female[MESH]|Humans[MESH]|Injections, Intra-Articular/methods[MESH]|Knee Joint/diagnostic imaging/drug effects/*surgery[MESH]|Male[MESH]|Middle Aged[MESH]|Osteoarthritis/drug therapy/physiopathology/surgery[MESH]|Radiography[MESH]|Retrospective Studies[MESH]|Steroids/administration & dosage/therapeutic use[MESH]|Time Factors[MESH]|Treatment Outcome[MESH]|Yttrium Radioisotopes[MESH] |