Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Antiviral resistance: mechanisms, clinical significance, and future implications Kimberlin DW; Whitley RJJ Antimicrob Chemother 1996[Mar]; 37 (3): 403-21The increased awareness of antiviral resistance over the past decade has paralleled the development of new antiviral agents. While such resistant viral isolates are of clinical significance primarily in immunocompromised individuals, the development and transmission of such mutants have been reported in immunocompetent persons as well. As antiviral agents are increasingly utilised by the clinician, the incidence of such occurrences is likely to increase. Issues relating to mechanisms of antiviral resistance, clinical manifestations and significance of resistance, and implications for future antiviral development and utilisation are reviewed in this article. Viruses that are discussed include herpes simplex virus, varicella-zoster virus, cytomegalovirus, influenza A virus, and human immunodeficiency virus.|Antiviral Agents/*pharmacology[MESH]|Cytomegalovirus/drug effects/genetics[MESH]|Drug Resistance, Microbial[MESH]|Forecasting[MESH]|HIV-1/drug effects/genetics[MESH]|Herpesvirus 3, Human/drug effects/genetics[MESH]|Humans[MESH]|Orthomyxoviridae/drug effects/genetics[MESH]|Simplexvirus/drug effects/genetics[MESH] |