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Transposable elements: how non-LTR retrotransposons do it Finnegan DJCurr Biol 1997[Apr]; 7 (4): R245-8The source of the enzyme activity responsible for the transposition of retrotransposons of the type that lack terminal repeats has at last been identified: in L1Hs elements, it is encoded by the second open reading frame and is a nuclease related to the apurinic repair endonucleases.|*Repetitive Sequences, Nucleic Acid[MESH]|*Retroelements[MESH]|Animals[MESH]|DNA Repair/genetics[MESH]|DNA-(Apurinic or Apyrimidinic Site) Lyase[MESH]|Deoxyribonuclease IV (Phage T4-Induced)[MESH]|Drosophila melanogaster/genetics/virology[MESH]|Genes, gag[MESH]|Genes, pol[MESH]|Humans[MESH]|Lyases/metabolism[MESH]|Models, Genetic[MESH]|Moloney murine leukemia virus/genetics[MESH]|Open Reading Frames[MESH]|RNA-Directed DNA Polymerase/metabolism[MESH]|Retroviridae/*genetics[MESH]|Saccharomyces cerevisiae/genetics/virology[MESH]|Sequence Deletion[MESH] |
