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lüll The Tom and Tim machine Pfanner N; Meijer MCurr Biol 1997[Feb]; 7 (2): R100-3Translocation of precursor proteins into mitochondria depends on loosely assembled protein complexes in the outer and inner membranes. Recent studies indicate that dynamic interactions of subcomplexes and cooperation with molecular chaperones drive key steps in protein import.|*Escherichia coli Proteins[MESH]|*Membrane Transport Proteins[MESH]|Adenosine Triphosphatases/metabolism[MESH]|Animals[MESH]|Bacterial Proteins/metabolism[MESH]|HSP70 Heat-Shock Proteins/metabolism[MESH]|Intracellular Membranes/metabolism[MESH]|Membrane Proteins/*metabolism[MESH]|Mitochondria/*physiology/*ultrastructure[MESH]|Models, Biological[MESH]|Protein Precursors/*metabolism[MESH]|Protein Processing, Post-Translational[MESH]|SEC Translocation Channels[MESH]|SecA Proteins[MESH] |