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Cell cycle: on target with Myc Zornig M; Evan GICurr Biol 1996[Dec]; 6 (12): 1553-6Recent evidence indicates that the c-Myc proto-oncogene activates transcription of cdc25A. The Cdc25A protein phosphatase is required both for progression through mitosis and for Myc-induced apoptosis, making cdc25A the most attractive Myc target gene identified so far.|*Gene Expression Regulation[MESH]|Animals[MESH]|Apoptosis[MESH]|Cell Cycle[MESH]|Cell Cycle Proteins/*genetics[MESH]|Helix-Loop-Helix Motifs[MESH]|Humans[MESH]|Leucine Zippers[MESH]|Phosphoprotein Phosphatases/*genetics[MESH]|Proto-Oncogene Mas[MESH]|Proto-Oncogene Proteins c-myc/*genetics/metabolism[MESH]|Trans-Activators/*genetics/metabolism[MESH]|cdc25 Phosphatases[MESH] |
