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lüll Late onset bone marrow transplant nephropathy Oyama Y; Komatsuda A; Imai H; Ohtani H; Hamai K; Wakui H; Miura AB; Nakamoto YIntern Med 1996[Jun]; 35 (6): 489-93We report a patient who exhibited proteinuria and renal failure 93 months after receiving an allogeneic bone marrow transplantation (BMT) from his HLA-identical brother. A renal biopsy specimen revealed segmental sclerosis, mesangiolysis, subendothelial lucency in the glomeruli, fibrosis and small round cell infiltration in the interstitium, and hyaline droplets in the intimal spaces of arterioles and small arteries. These histological findings were consistent with late onset BMT nephropathy. This nephropathy may represent a more serious problem in the near future in Japan, since the number of BMT performed has been increasing with the establishment of a bone marrow bank.|*Bone Marrow Transplantation/adverse effects/statistics & numerical data[MESH]|Adult[MESH]|Antineoplastic Combined Chemotherapy Protocols/therapeutic use[MESH]|Combined Modality Therapy[MESH]|Cyclosporine/*adverse effects[MESH]|Graft vs Host Disease/etiology/pathology[MESH]|Humans[MESH]|Immunosuppressive Agents/*adverse effects[MESH]|Kidney Failure, Chronic/chemically induced/epidemiology/*etiology/pathology[MESH]|Kidney/pathology[MESH]|Leukemia, Myeloid, Acute/drug therapy/therapy[MESH]|Male[MESH]|Proteinuria/etiology[MESH]|Radiation Injuries/*etiology/pathology[MESH]|Time Factors[MESH]|Transplantation Conditioning/*adverse effects[MESH]|Whole-Body Irradiation/*adverse effects[MESH] |