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"Hibernating" myocardium: asleep or part dead?Armstrong WFJ Am Coll Cardiol 1996[Aug]; 28 (2): 530-5Chronic ischemic dysfunction of the left ventricle is commonly presumed to represent "hibernating" myocardium. The implication of this assumption is that with successful reperfusion, systolic function will improve. Several diagnostic techniques including dobutamine stress echocardiography have been used to detect "viable" myocardium in the setting of chronic left ventricular dysfunction. Predictive accuracies of 70% to 85% have been reported for identifying myocardium that recovers function. Recovery of function has been variable and often dependent on the severity of dysfunction. All current models have presumed that chronically dysfunctioning myocardium is "hibernating." Obviously, in the chronic setting, dysfunction may have many causes and include components of transmural and nontransmural infarction as well as hibernating myocardium. This review focuses on the independent role that nontransmural infarction may play in chronic dysfunction and suggests its impact on diagnostic techniques used to identify hibernating myocardium.|*Myocardial Infarction[MESH]|*Myocardial Ischemia[MESH]|*Myocardial Stunning[MESH]|*Ventricular Dysfunction, Left[MESH]|Animals[MESH]|Coronary Disease[MESH]|Dobutamine[MESH]|Echocardiography[MESH]|Heart/diagnostic imaging[MESH]|Humans[MESH]|Myocardial Contraction[MESH]|Radionuclide Imaging[MESH] |
