Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Selenium and the thyroid: how the relationship was established Corvilain B; Contempre B; Longombe AO; Goyens P; Gervy-Decoster C; Lamy F; Vanderpas JB; Dumont JEAm J Clin Nutr 1993[Feb]; 57 (2 Suppl): 244S-248SSeveral hypotheses concerning consequences of selenium deficiency on iodine metabolism can be proposed on the basis of experimental studies in rats and from epidemiological and experimental studies in humans. By decreasing intracellular GSH peroxidase activity, selenium deficiency may increase hydrogen peroxide (H2O2) supply and lead over several weeks to the thyroid atrophy observed in myxoedematous cretins. By improving thyroid hormone synthesis and by decreasing peripheral thyroxin (T4) deiodination, selenium deficiency could protect fetal brain T4 supply and thus prevent neurologic cretinism. Selenium deficiency may protect against iodine deficiency by decreasing T4 metabolism--and thus iodide leakage and--perhaps also by increasing H2O2 supply and thyroid hormone synthesis and thus thyroid efficiency.|Animals[MESH]|Humans[MESH]|Hydrogen Peroxide/metabolism[MESH]|Iodide Peroxidase/metabolism[MESH]|Iodine/deficiency[MESH]|Selenium/*deficiency/therapeutic use[MESH]|Thyroid Gland/*metabolism[MESH]|Thyroid Hormones/*metabolism[MESH] |
