Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Selenium deficiency, thyroid hormone metabolism, and thyroid hormone deiodinases Arthur JR; Nicol F; Beckett GJAm J Clin Nutr 1993[Feb]; 57 (2 Suppl): 236S-239SMuch research into the functions of selenium in the cell has concentrated on its role in selenium-containing glutathione peroxidases. However, selenium was recently shown to be an essential component of type I iodothyronine 5'-deiodinase in rats, which converts thyroxin to the more biologically active hormone 3,5,3'-triiodothyronine. Thus, selenium-deficient rats have low tissue deiodinase activities and abnormal thyroid hormone metabolism. The discovery of this function for selenium in thyroid hormone metabolism has important implications for the interpretation of the effects of selenium deficiency, especially in individuals with an adequate vitamin E status.|Animals[MESH]|Humans[MESH]|Iodide Peroxidase/*metabolism[MESH]|Selenium/*deficiency/physiology[MESH]|Thyroid Gland/metabolism[MESH]|Thyroid Hormones/*metabolism[MESH]|Thyroxine/metabolism[MESH]|Triiodothyronine/metabolism[MESH] |
