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lüll HIV in the oral cavity: virus, viral inhibitory activity, and antiviral antibodies: a review Malamud D; Friedman HMCrit Rev Oral Biol Med 1993[]; 4 (3-4): 461-6Although it is generally assumed that HIV transmission does not occur through casual oral contact, persistent reports in the literature and the well-documented case of the Florida dentist (Ou et al., 1992) have served to elevate concerns and interest about the possibility of oral transmission of HIV. The literature suggests that: (1) the presence of infectious virus in the oral cavity is an uncommon event; (2) PCR data indicate that HIV sequences may be present in the oral cavity at reasonably high frequency--further studies are warranted; (3) saliva appears to contain potent anti-HIV activity that may be responsible for the low oral virus titer; and (4) oral secretions are a reliable source for monitoring anti-HIV antibodies. It is clear that the oral cavity will remain a focus for HIV research, in terms of both viral transmission/pathogenesis and for noninvasive diagnosis of the HIV-positive individual.|Antiviral Agents/*physiology[MESH]|HIV Antibodies/*analysis[MESH]|HIV/*immunology/*physiology[MESH]|Humans[MESH]|Mouth/*microbiology[MESH]|Saliva/*immunology/*physiology[MESH] |