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Copper pumping ATPases: common concepts in bacteria and man Solioz M; Odermatt A; Krapf RFEBS Lett 1994[Jun]; 346 (1): 44-7Recently, four genes encoding putative copper pumping ATPases have been cloned from widely different sources: two genes from Enterococcus hirae that are involved in copper metabolism and two human genes that are defective in the copper-related Wilson and Menkes disease. The predicted gene products are P-type ATPases. They exhibit extensive sequence similarity and appear to be members of a new class of ATP driven copper pumps involved in the regulation of cellular copper.|Adenosine Triphosphatases/chemistry/genetics/*metabolism[MESH]|Amino Acid Sequence[MESH]|Bacteria/*enzymology[MESH]|Copper/*metabolism[MESH]|Enterococcus/enzymology/genetics[MESH]|Hepatolenticular Degeneration/enzymology/genetics[MESH]|Humans[MESH]|Menkes Kinky Hair Syndrome/enzymology/genetics[MESH]|Molecular Sequence Data[MESH]|Protein Folding[MESH] |
