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lüll Medical consequences of cocaine Gray JDCan Fam Physician 1993[Sep]; 39 (ä): 1975-6, 1979-81Cocaine use among middle-class North Americans increased dramatically during the 1980s. Medical complications involve almost every organ system and are produced by intense vasoconstriction. Managing cocaine-induced disease requires careful identification and the use of alpha-adrenergic blocking agents, in addition to standard therapy and referral to specialists to manage cocaine withdrawal.|Adrenergic alpha-Antagonists/therapeutic use[MESH]|Adult[MESH]|Cocaine/*adverse effects/metabolism[MESH]|Comorbidity[MESH]|Female[MESH]|Humans[MESH]|Infant, Newborn[MESH]|Male[MESH]|North America/epidemiology[MESH]|Pregnancy[MESH]|Referral and Consultation[MESH]|Social Problems[MESH]|Substance Withdrawal Syndrome/*prevention & control[MESH]|Substance-Related Disorders/*complications/diagnosis/epidemiology/metabolism/therapy[MESH] |