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Usher s syndrome and multiple sclerosis Review of an individual with Usher s syndrome with a multiple sclerosis-like illness Lynch SG; Digre K; Rose JWJ Neuroophthalmol 1994[Mar]; 14 (1): 34-7We describe an individual with Type I Usher's syndrome and a multiple sclerosis-like illness. MRI scan showed vermian atrophy on T1-weighted images and multiple white matter lesions in the periventricular areas on T2-weighted images. Although MRIs demonstrating increased signal intensity on weighted images are reported in some individuals with Usher's syndrome, the cerebrospinal fluid findings are not described in these cases. In the present case, oligoclonal bands were present in the spinal fluid. The possibility of a linkage between the two diseases is raised.|Adult[MESH]|Brain/pathology[MESH]|Fundus Oculi[MESH]|Hearing Loss, Sensorineural/*complications/congenital/diagnosis[MESH]|Humans[MESH]|Magnetic Resonance Imaging[MESH]|Male[MESH]|Multiple Sclerosis/*complications/diagnosis[MESH]|Retinitis Pigmentosa/*complications/congenital/diagnosis[MESH]|Syndrome[MESH]|Visual Acuity[MESH] |
