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lüll Meta-analysis and its problems Eysenck HJBMJ 1994[Sep]; 309 (6957): 789-92Including all relevant material--good, bad, and indifferent--in meta-analysis admits the subjective judgments that meta-analysis was designed to avoid. Several problems arise in meta-analysis: regressions are often non-linear; effects are often multivariate rather than univariate; coverage can be restricted; bad studies may be included; the data summarised may not be homogeneous; grouping different causal factors may lead to meaningless estimates of effects; and the theory-directed approach may obscure discrepancies. Meta-analysis may not be the one best method for studying the diversity of fields for which it has been used.|*Meta-Analysis as Topic[MESH]|Data Collection[MESH]|Humans[MESH]|Multivariate Analysis[MESH]|Regression Analysis[MESH]|Selection Bias[MESH]|Sensitivity and Specificity[MESH] |