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Role of heterotrimeric GTP binding proteins in vesicular protein transport: indications for both classical and alternative G protein cycles Helms JBFEBS Lett 1995[Aug]; 369 (1): 84-8Heterotrimeric G proteins are involved in hormonal signal transduction across the plasma membrane. Recent evidence suggests that they have a role in vesicular protein transport as well. Biochemical probes that interfere with the classical G protein cycle have been applied to the field of intracellular membrane transport to study their mechanism of action. Evidence has been obtained that intracellular G proteins act both through classical and alternative G protein cycles.|*Signal Transduction[MESH]|Biological Transport[MESH]|Cell Membrane/*metabolism[MESH]|Endocytosis/physiology[MESH]|GTP-Binding Proteins/*metabolism[MESH]|Guanosine Triphosphate/*metabolism[MESH]|Intracellular Membranes/*metabolism[MESH]|Models, Biological[MESH]|Organelles/metabolism[MESH]|Protein Conformation[MESH]|Proteins/metabolism[MESH] |
