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lüll Management of ductal carcinoma in situ of the breast Carty NJ; Carter C; Royle GT; Johnson CDAnn R Coll Surg Engl 1995[May]; 77 (3): 163-7The advent of mammographic breast screening has increased the detection of ductal carcinoma in situ (DCIS), which now accounts for 15-20% of all breast cancer. While symptomatic DCIS has been treated satisfactorily by mastectomy, this may be an overtreatment of smaller screen-detected lesions. Although local excision, with or without radiotherapy, is associated with a significant risk of local recurrence of DCIS or invasive cancer, salvage surgery is usually successful. The long-term breast-specific mortality rate of treatment by mastectomy and local excision are similar. Whereas mastectomy is still appropriate for women with lesions > 30 mm in diameter or centrally placed and for those women who demand the best possible disease-free survival, local surgery should otherwise be considered.|Breast Neoplasms/radiotherapy/*surgery[MESH]|Carcinoma in Situ/radiotherapy/*surgery[MESH]|Carcinoma, Ductal, Breast/radiotherapy/*surgery[MESH]|Female[MESH]|Humans[MESH]|Mass Screening[MESH]|Mastectomy/*methods[MESH]|Neoplasm Recurrence, Local[MESH]|Radiotherapy, Adjuvant[MESH] |