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Radiation-induced primary brain lymphoma: a case report Stein ME; Haim N; Ben-Shachar M; Goldsher D; Bernstein Z; Ben-Arieh Y; Kuten ATumori 1995[May]; 81 (3): 204-7A patient who developed primary brain lymphoma 6 years following whole brain irradiation due to a low-grade glioma is described. The patient had no evidence of congenital or acquired immunodeficiency state and achieved a good and prompt response to aggressive chemotherapy, including high-dose methotrexate. The previous radiation therapy is implicated in the etiology of the lymphoma because of the geometric coincidence, the relatively long latency period and the different histology. A brief review of current literature is reported.|Adult[MESH]|Brain Neoplasms/*etiology/pathology/*radiotherapy[MESH]|Glioma/*radiotherapy[MESH]|Humans[MESH]|Lymphoma/*etiology/pathology[MESH]|Male[MESH]|Neoplasms, Radiation-Induced/*etiology/pathology[MESH]|Neoplasms, Second Primary/*etiology/pathology[MESH]|Radiotherapy/adverse effects[MESH] |
