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Type III glycogenosis presenting as liver disease in adults with atypical histological features Fellows IW; Lowe JS; Ogilvie AL; Stevens A; Toghill PJ; Atkinson MJ Clin Pathol 1983[Apr]; 36 (4): 431-4Two cases of type III glycogen storage disease are reported in adults; the occurrence of cirrhosis in one case illustrates the potential development of chronic liver disease in this condition. The other was the oldest patient with this condition found in a review of published reports. Electron microscopy of peripheral blood leucocytes to demonstrate excess glycogen was found to be a quick and useful aid to diagnosis. Histology of these adult cases showed a distribution of hepatocyte vacuolation which has not been previously recorded.|Adult[MESH]|Aged[MESH]|Glycogen Storage Disease Type III/*complications/pathology[MESH]|Glycogen Storage Disease/*complications[MESH]|Glycogen/analysis[MESH]|Humans[MESH]|Leukocytes/ultrastructure[MESH]|Liver Diseases/*etiology/pathology[MESH]|Liver/pathology[MESH]|Male[MESH] |
